Showing posts with label Side Effects. Show all posts
Showing posts with label Side Effects. Show all posts

Ibuprofen causing Infertility in Men !

Ibuprofen, which is an over-the-counter medicine and commonly used as pain killer around the globe, is recently described as male fertility killer. Decreasing fertility in humans is becoming a topic of concern for scientific community. The latest research was conducted in University of Copenhagen, which suggested that long term usage of Ibuprofen can result in decreased production of male hormone Testosterone. Ibuprofen can reversibly hinder the production of testosterone at both tissue and cellular levels by testicular cells.

An earlier research suggested that aspirin, acetaminophen (also known as paracetamol) and ibuprofen affects the testicles of male babies inside the mother's womb if she is taking them while pregnant. Ibuprofen has the strongest effect, out the above mentioned three medicines. This research inspired researchers in University of Copenhagen to target their research on effect of Ibuprofen on adults. Testicles are not only responsible for sperm production but also for testosterone hormone production. Testosterone is responsible for all manly things in man like muscles and fertility. Ibuprofen is not only used by common man. Athletes and sportsperson also use it as a pain killer, for whom testosterone means a lot.

Shall i totally stop taking Ibuprofen ?
No, the negative effect is only if you take it continuously for longer duration. So if you need to take it for more than three days then you must consult your doctor. A number of other researches will be conducted on the same topic to cross check the results. But still if you have any fear in using it then you may ask your doctor to prescribe some alternate pain killer.

The younger participants in the research who took Ibuprofen for a shorter period, the negative effect can be reversed. But those who are above 40 and taking Ibuprofen for a long time should worry.

Some facts to open your eyes about increasing infertility in human race.

  • 15% of all couples around the globe in 2010 were infertile.
  • Sperm counts of men in North America, Europe, Australia and New Zealand declined by 59% from 1971 to 2011.

Nobody know the exact cause of this increasing infertility. But there is something wrong either with what we eat or what we use to protect ourselves from some diseases. Drugs are often known for their side-effects, which is never mentioned when they are prescribed. Even the manufacturers of these drugs don't print anything about the side effects. Usually medicines are not tested for their effect on the reproductive system of humans. But now the time has come to make some changes. Increasing user awareness can make the difference.
The results of this research has opened the eyes of a number of people as Ibuprofen is the most widely used pain killer around the world.

Some Medicines cause Acute Kidney Failure

Yes, you heard it right. Some medicines which are used to treat other medical conditions may result in Acute Kidney Failure. If correct treatment is provided at right time then such Acute Kidney Failure is reversible. Some antibiotics, blood pressure medicines, cancer treatment medicines, medical dyes (used in contrast imaging), HIV medicines, nonsteroidal anti-inflammatory drugs, ulcer medicines and some illegal drugs (such as heroin) can cause acute kidney failure.

Some common Acute Kidney Failure symptoms are:
  • Decreased Urine Output
  • Fluid retention, that can cause swelling your legs,ankle and feet.
  • Other symptoms like drowsiness, shortness of breath, fatigue, confusion, nausea and chest pain are also common in some other diseases.
  • Sometimes there are no visible symptoms but only lab tests can detect kidney failure.

25% of Acute Kidney Failure are attributed to medicines used to treat some other disease. If you ever feel some symptoms of mild kidney failure while taking some medication, then you should discuss it with your doctor.
Some common medicines that are known to cause Acute Kidney Failure are:
  • NSAIDS (Nonsteroidal Anti-Inflammatory Drugs) such as ibuprofen, naproxen, Motrin, Aleve, and Advil. They reduce blood flow to kidneys which can cause Acute Kidney Failure.
  • Diuretics, also known as water pills, changes water balance in body and thus interferes with kidney function. Jardiance (empagliflozin) is a diabetes medicine which also have diuretic effect and may cause kidney failure.
  • ACE Inhibitors (such as Lisinopril, Enalaril, and Ramipril) are usually used to treat high blood pressure and heart failure. Names of these medicines usually end with "-il".
  • Chemotherapy medicines used for cancer treatment such as cisplatin, carboplatin, and methotrexate.
  • Some antibiotics cause swelling in kidney and cause kidney failure.
  • Apart from the above mentioned medicines there are numerous others that can cause kidney damage. Some are them are used in treatment of AIDS, cancer, osteoporosis, ulcers and numerous other diseases.

The motive of this article is not mean that you should not take the above listed medicines. Most of the above listed medicines are life saving drugs. But proper usage of these drugs and taking them only on doctor's prescription is necessary if you want to save yourself from any such side effect. Almost all medicines have some side effects associated with them. To save yourself from those side effects it is necessary to take them as prescribed by doctor. You should also keep yourself educated about the medicines you are taking on prescription. Even if you take some vitamin and mineral supplement to keep yourself fit, then you make sure that you know all possible outcomes of that medicine.

Prednisone 20 mg Tablet Side effects and Overdose symptoms


Prednisone is a corticosteroid which suppress the immune system and helps in reduction of release of those compounds in body which causes inflammation. Prednisone is anti-inflammatory and immunosuppressant medicine. Usually its available in the form of a 1, 2, 5 and 20mg tablet.

Usually 5 mg daily dose is the physiologic dose for adults. But in some cases Prednisone 20mg can also be recommended. Never decide you dose on your own. Stick to the dosage told by doctor.

Prednisone is used to treat following medical conditions:

  • allergic disorders
  • skin conditions
  • ulcerative colitis
  • arthritis
  • lupus
  • psoriasis
  • breathing disorders

Prednisone 20 mg Side Effects

Prednisone is an Asteroid and its the basic side effect of steroids that them weaken our immune system and make our body prone to catching infection. Some common side effects of Prednisone are

  • shortness of breath
  • vision problems
  • severe pain in your upper stomach
  • severe depression
  • bloody or tarry stools
  • eye pain
  • changes in personality or behavior
  • slow wound healing
  • sleep problems (insomnia)

Long Term Usage Side Effects of Prednisone

  • It can cause bone-loss (osteoporosis), especially if you smoke while taking Prednisone. Its necessary to take have diet rich in Vitamin D and Calcium to protect yourself from this side effect.
  • It can cause thinning of skin and easy bruising.
  • Sometimes it causes changes in the shape or location of body fat in your face, neck, back, and waist. It can also increase acne or facial hair
  • Prednisone long-term usage can also cause menstrual problems, impotence, or loss of interest in sex.

Precautions to be used  while taking Prednisone

  • Never stop taking Prednisone suddenly. Its dose should be reduced gradually as per the advice of a doctor.
  • Never use Prednisone if you are suffering from any type of fungal infection.
  • Prednisone can worsen the condition if you are already suffering from any infection or recovered from an infection in past few weeks. So if your doctor is prescribing Prednisone then he/she might ask you about your medical condition in past few weeks.
  • Usually Prednisone is not prescribed from pregnant women, as it can affect the growth of unborn baby.
  • Prednisone can cause some medical test results to be unusual.
  • Try to keep yourself away from sick people as you are more prone to diseases (Prednisone is an immuno-suppresant).
  • Prednisone should be taken with food or milk to prevent stomach upset.

Prednisone Overdose

Prednisone overdose does not cause any life-threatening condition. However these are some side-effects of long term usage which are discussed above. If you forget to take a dose then take it as soon as you remember, but if its almost time for your next dose then leave it. Never double your dose to makeup for a missed dose.

What are Paracetamol Tablet's Side Effects ?

Paracetamol is one of the most used medicine when you are suffering from fever. People don't even think twice before taking Paracetamol Tablet to get relief from fever. But we never take care of side effects of Paracetamol. They don't ever think that Paracetamol can harm their body in any way. But the truth is that, like all other medicines Paracetamol too have some side effects. And over usage of Paracetamol is very harmful for human body. Have you ever thought - What are Paracetamol Tablet's Side Effects?

Paracetamol is available as tablets for adults and as Syrup for children under different brand names. Everybody use it without any prescription from doctor. We take it even during mild fever, so that the condition shouldn't get worse. Here is providing list of side effects of Paracetamol.

Side Effects of  Paracetamol

  • Acetaminophen is an active ingredient in Paracetamol, which is the primary reason for most of the side effects. Alcoholic patients may face hepatotoxicity even after normal dose of Acetaminophen.
  • Acetaminophen overdose can cause severe liver injury which is recoverable. According to a research, around 7% patients, who were given overdose of Paracetamol due to to medical reasons faced Liver Injury.
  • Gastrointestinal side effects such as vomiting and nausea have been also reported.
  • Respiratory side effects have also been been noticed. Eosinophilic Pneumonia is also noticed in a few rare cases.
  • Cardiovascular side effects like hypertension and hypotension have been noticed in a few cases.
  • Skin Rashes is also side effect of Paracetamol. 
  • Nervous System side effects like headache is noticed in 10% patients, insomnia is noticed as side effect in 7% patients, and fatigue is also noticed in few cases.
  • Acetaminophen present in Paracetamol is also known to initiate anxiety.
After reading this article you will definitely think twice before taking Paracetamol. We are not stopping you from taking Paracetamol to get relief from fever, but we will suggest you to not use it in mild fever. If your fever is going above 100 degree F, then you should use it. Bad effect of Paracetamol on your Kidney and lever, which are one of the most important organs of human body, made us write this article for your better health. We will bring you more better health facts in our upcoming articles.

Side Effects of Paracetamol during Pregnancy

Usually Paracetamol don't have any adverse effect during Pregnancy. You might take mild doses of it if you feel high fever or Pain. But before taking high doses of Paracetamol must consult your doctor. Salts in Paracetamol may react with other medicines that you may be taking during pregnancy. Sometimes Paracetamol comes with Caffeine, which is dangerous during pregnancy. Caffeine have very adverse side effect on growth of unborn child. It may make unborn child underweight.

E Cigarette Side Effects

E Cigarette were introduced in 2007 to the UK market. However they were invented by a Chinese Chemist in year 2003. The restriction on tobacco products take people addicted to cigarette to this new version of cigarette which is not banned by any law as it don't contain tobacco.

The only benefit of this e cigarette is that its tobacco free, which means no harmful tar and carbon monoxide. When we hear about these benefits we think that there are no side effects of e cigarette. We don't try to know how it works and what it contains. So here we will discuss some major e cigarette side effects. E cigarette side effects are both medical and social and both should be considered with equal attention as tobacco products were banned taking safety of whole society into consideration.

E Cigarette Side Effects  

  • The most dangerous thing in an e cigarette is nicotine. And its not healthy. Its the same constituent of a cigarette which makes people addicted to it.
  • There is no ban on nicotine so people will use it more and become more addicted. 
  • There is no age restriction in using e cigarette so minors are also using it in full flow. This is the worst E cigarette side effect.
  • Its cost of usage is another e cigarette side effect. However in some countries the cost of e cigarette is less but in some countries it costs much more than usual cigarettes. It directly affects the economy of a simple household.
  • Some new users of e cigarette face side effects like nausea, sweating, increased heart rate and jitters.
  • Long term effects of e cigarette are still being studied so its quiet early to say that they are really safe. However you can say that they are safer than traditional cigarette but e cigarette also have side effects.

Lisinopril Dosage (5mg, 10mg, 20mg) Side Effects

Lisinopril is an effective high blood pressure medicine and commonly used by patients who have survived after a heart attack. Lisinopril is an ACE (Angiotensin Converting Enzyme). Lisinopril is easily available in 5mg, 10mg and 20mg dosage. You can take it with or without taking food. It should be stored away from moisture and heat. Never increase or decrease the dosage without consulting the doctor. Use of this medicine is strictly prohibited for pregnant ladies and diabetic people.

Lisinopril Dosage

Lisinopril Dosage should be taken in correct amount, otherwise it may be harmful for your health. Its 5mg, 10mg ans 20mg tablets are available in market. Its dosage should be appropriate according to your type of disease and age. Lisinopril Dosage mentioned here are just an estimated value based on normally prescribed values. But we strongly recommend you to get a prescription from a good doctor before taking this medicine.

Lisinopril Dosage for Adults (Hypertension)

Initial Dosage: 10 mg (OD) Once a Day.
Normal Dosage: 20 to 40 mg (OD) Once a Day.

Lisinopril Dosage for Old People (Hypertension)

Initial Dosage: 2.5 to 5 mg (OD) Once a Day.
Increase at 2.5 to 5 mg/day increments after every one or two weeks.
Maximum dose: 40 mg/day.

Lisinopril Dosage for Children (Hypertension)

For children upto 6 years of age:
Initial dose: 0.07 mg/kg of body weight OD (once daily).
Maximum initial dose is 5 mg (OD) Once a Day
Maintenance dose: Dosage should be adjusted according to BP (blood pressure) response after every one or two weeks.
Maximum dose: Doses above 0.61 mg/kg or greater than 40 mg have not been studied in pediatric patients.

Usual Adult Dose for Congestive Heart Failure

Initial dose: 5 mg orally OD (once daily). (If patient is diuretic, then the diuretic dose should be reduced).
Maintenance dose: 5 to 20 mg orally  OD (once daily).

Usual Adult Dose for Myocardial Infarction:

Initial dose: 5 mg orally (within 24 hours of the onset of acute myocardial infarction).
Subsequent doses: 5 mg orally after 24 hours.
10 mg orally after 48 hours.
Maintenance dose: 10 mg orally  OD (once daily). This dose should continue for 42 days, i.e 6 weeks.

Patients with a low systolic blood pressure (<=120 mm Hg) should must consult a doctor before taking Lisinopril.

Usual Adult Dose for Diabetic Nephropathy

Initial dose: 10 to 20 mg orally  OD (once daily).
Maintenance dose: 20 to 40 mg orally  OD (once daily).

Lisinopril Side Effects

Sometimes Lisinopril may cause some serious side effects. Thats why the initial dosage is kept low for all type of patients. Even you you feel some allergic reactions the don't hesitate in consulting your doctor immediately. 
Some of these side effects may be difficulty in breathing, severe stomach pain, swelling on your face, lips, tongue, or throat.

Call your doctor immediately if you face any of the following side effects:
  • A light-headed feeling, like you might pass out; 
  • swelling, rapid weight gain
  • fever, chills, body aches( flu symptoms)
  • tired feeling, muscle weakness
  • Slow heart rate, weak pulse
  • Less or no urination
  • Uneven heartbeats 
  • psoriasis (raised, silvery flaking of the skin)
  • chest pain
  • Muscle weakness, Tingly feeling 

Common lisinopril side effects may include depressed mood, headache, mild skin itching, upset stomach and Cough.

Precautions before using Lisinopril

  • Pregnant ladies should not use Lisinopril as it may harm unborn kid. If you are already using Lisinopril and got the good news of getting pregnant then immediately stop taking it and consult your doctor.
  • Lisinopril is also not prescribed to diabetic people as it may react with some salts present in the medicines used by diabetic patients.
  • Kidney patients should also avoid using it.
  • Consult your doctor if you are breast feeding a baby.
  • If you are going to be operated for some thing, they you may need to stop taking Lisinopril for some time.
  • Don't use liquor while you are on Lisinopril as it may lower your Blood Pressure to a dangerous level.
If you miss a dose then don't double you next dose. Its better to skip a missed dose.

Epilim Chrono Weight Gain Side Effects (500 mg, 300mg, 200mg Tablets)

Epilim Chrono

Epilim Chrono is basically Sodium valproate. This medicine comes in 500 mg, 300 mg and 200 mg. Its is widely used mood stabilizer. Epilim Chrono contains Sodium valproate which stabilizes electrical activity in human brain. Epilim Chrono is used to treat:

  • Epilepsy 
  • Panic attack
  • Anxiety disorder 
  • Posttraumatic Stress Disorder
Epilim Chrono should not be used by women during pregnancy as it can cause birth defects.

Epilim Chrono Weight Gain Tablets

Epilim Chrono tablet's major side effect is weight gain. That why some people try to use it as a weight gain tablet. strongly suggest you to use these tablets only after consulting a doctor.

Epilim Chrono Side Effects

Epilim Chrono is known for its side effects from past few years. Some of its common side effects are
Gastrointestinal Disturbances
Reversible Hair Loss

Myolastan Tetrazepam Side Effects (50 mg)

Myolastan is basically Tetrazepam which is also marketed under various other names such as Clinoxan, Epsipam. It is a derivative of benzodiazepine. Properties of Myolastan include following :
  • Anxiolytic
  • AntiConvulsant
  • Hypnotic
  • Muscle relaxant

Myolastan 50 mg

Myolastan 50 mg is one of the most sold medicines for the properties mentioned above. It is used widely in european countries for following medical conditions.
  • Panic attacks
  • Muscle Spasm
  • Anxiety Disorders
  • Depression
But currently people are facing various side effects due to this medicine.

Myolastan Side Effects

Myolastan Side Effects include Sedative Effect. Its marketing is suspended by European Union during April 2013. Myolastan is also found allergic to skin in some cases.

Diabetes Side Effects in Men and Women on Brain Eyes and Skin

Diabetes Side Effects in Men & Women

Diabetes is well known for its side effects. In this disease the patient not only need to take care of his/her diet but also take care of side-effects caused by diabetes. One major well known side effect is on fresh wounds, as it take a long time for clotting to happen. So major injuries can result in high blood loss. Here will tell you some other side effects of diabetes and precautions that you can use to get over them.

Diabetes Side Effects

  • In a diabetic person the sugar level might get low as well, so he/she should always keep some sugar product handy to eat (especially when they are out of your home).
  • It takes longer to heal an injury. In diabetic person both clotting and healing process are slowed down. It might be 2 to 10 times slower than normal person. The speed of healing process also depends on your sugar level. It better to keep a first aid kit and dressing material handy. Avoid injuries but still if something happens wrong then don't wait for blood to stop, instead use the dressing material to stop the blood flow.
  • Another side effect of diabetes is on eyesight . If at any point of time you feel blurred vision or continuous pain in your head then consult your doctor as it might be symptom of eyesight problem.
  • People who don't take care of their diet and medicines instead of being diabetic, might face a kidney failure in their life. This is the worst thing that a diabetic person might face. 

Don't get feared by all these side effects, as if you take a balanced diet suggested by your doctor and proper medication, then you can easily get over these side effects. The side effects discussed above are common in men and women. In next update we will discuss more about separate side effects of diabetes in men and women.